Symbol: Name: ID: |
TNFRSF9 tumor necrosis factor receptor superfamily, member 9 GFS:1736 |
Gene name: | TNFRSF9 |
Chromosome: | 1p36 |
Previous Symbols: | ILA |
Previous Names: | |
Aliases: | CD137, 4-1BB |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1101059 | Rat Genome Database ID: | RGD:1598208 |
HGNC ID: | HGNC:11924 | RefSeq IDs: | NM_001561 |
Entrez Gene ID: | 3604 | Ensembl Gene ID: | ENSG00000049249 |
VEGA IDs: | OTTHUMG00000001223 | UniProt ID: | Q07011 |
UCSC ID: | uc001aot.2 | OMIM ID: | 602250 |
Pubmed: | PMID8262389 PMID 8639902 | ||
CCDS IDs: | CCDSCCDS92.1 |
The protein encoded by TNFRSF9 is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB. [provided by RefSeq]. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Receptor for TNFSF14/4-1BBL. Possibly active during T cell activation
Products for TNFRSF9 gene
Catalog | Product Name | Application | Company |
GFS:E01736 | tumor necrosis factor receptor superfamily, member 9; ELISA kit | ELISA | n/a |
GFS:A01736 | tumor necrosis factor receptor superfamily, member 9; Anti | ANTIBODIES | n/a |
GFS:P01736 | tumor necrosis factor receptor superfamily, member 9; Protien | Protien | n/a |