Symbol: Name: ID: |
TNFRSF4 tumor necrosis factor receptor superfamily, member 4 GFS:1729 |
Gene name: | TNFRSF4 |
Chromosome: | 1p36 |
Previous Symbols: | TXGP1L |
Previous Names: | |
Aliases: | ACT35, OX40, CD134 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:104512 | Rat Genome Database ID: | RGD:3920 |
HGNC ID: | HGNC:11918 | RefSeq IDs: | NM_003327 |
Entrez Gene ID: | 7293 | Ensembl Gene ID: | ENSG00000186827 |
VEGA IDs: | OTTHUMG00000001415 | UniProt ID: | P43489 |
UCSC ID: | uc001ade.2 | OMIM ID: | 600315 |
Pubmed: | PMID7510240 PMID 2828930 | ||
CCDS IDs: | CCDSCCDS11.1 |
The protein encoded by TNFRSF4 is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Products for TNFRSF4 gene
Catalog | Product Name | Application | Company |
GFS:E01729 | tumor necrosis factor receptor superfamily, member 4; ELISA kit | ELISA | n/a |
GFS:A01729 | tumor necrosis factor receptor superfamily, member 4; Anti | ANTIBODIES | n/a |
GFS:P01729 | tumor necrosis factor receptor superfamily, member 4; Protien | Protien | n/a |