Symbol: Name: ID: |
TNFRSF10D tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain GFS:1718 |
Gene name: | TNFRSF10D |
Chromosome: | 8p21 |
Previous Symbols: | |
Previous Names: | |
Aliases: | DcR2, TRUNDD, TRAILR4, CD264 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | Rat Genome Database ID: | ||
HGNC ID: | HGNC:11907 | RefSeq IDs: | NM_003840 |
Entrez Gene ID: | 8793 | Ensembl Gene ID: | ENSG00000173530 |
VEGA IDs: | OTTHUMG00000097845 | UniProt ID: | Q9UBN6 |
UCSC ID: | uc003xcz.1 | OMIM ID: | 603614 |
Pubmed: | PMID9382840 PMID 9537512 | ||
CCDS IDs: | CCDSCCDS6038.1 |
Tumor necrosis factor receptor superfamily member 10D is a protein that in humans is encoded by the TNFRSF10D gene. The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain, a transmembrane domain, and a truncated cytoplamic death domain. This receptor does not induce apoptosis, and has been shown to play an inhibitory role in TRAIL-induced cell apoptosis. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Receptor for the cytotoxic ligand TRAIL. Contains a truncated death domain and hence is not capable of inducing apoptosis but protects against TRAIL-mediated apoptosis. Reports are contradictory with regards to its ability to induce the NF-kappa-B pathway. According to PubMed:9382840, it cannot but according to PubMed:9430226, it can induce the NF-kappa-B pathway.
Products for TNFRSF10D gene
Catalog | Product Name | Application | Company |
GFS:E01718 | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain; ELISA kit | ELISA | n/a |
GFS:A01718 | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain; Anti | ANTIBODIES | n/a |
GFS:P01718 | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain; Protien | Protien | n/a |