Symbol: Name: ID: |
TNFRSF17 tumor necrosis factor receptor superfamily, member 17 GFS:1724 |
Gene name: | TNFRSF17 |
Chromosome: | 16p13.1 |
Previous Symbols: | BCMA |
Previous Names: | |
Aliases: | BCM, CD269 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1343050 | Rat Genome Database ID: | RGD:1304703 |
HGNC ID: | HGNC:11913 | RefSeq IDs: | NM_001192 |
Entrez Gene ID: | 608 | Ensembl Gene ID: | ENSG00000048462 |
VEGA IDs: | OTTHUMG00000129826 | UniProt ID: | Q02223 |
UCSC ID: | uc002dbv.2 | OMIM ID: | 109545 |
Pubmed: | PMID1396583 PMID 8165126 | ||
CCDS IDs: | CCDSCCDS10552.1 |
Tumor necrosis factor receptor superfamily member 17 is a protein that in humans is encoded by the TNFRSF17 gene. The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK.
Products for TNFRSF17 gene
Catalog | Product Name | Application | Company |
GFS:E01724 | tumor necrosis factor receptor superfamily, member 17; ELISA kit | ELISA | n/a |
GFS:A01724 | tumor necrosis factor receptor superfamily, member 17; Anti | ANTIBODIES | n/a |
GFS:P01724 | tumor necrosis factor receptor superfamily, member 17; Protien | Protien | n/a |