Symbol: Name: ID: |
TNFRSF14 tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) GFS:1723 |
Gene name: | TNFRSF14 |
Chromosome: | 1p36.32 |
Previous Symbols: | |
Previous Names: | |
Aliases: | HVEM, ATAR, TR2, LIGHTR, HVEA |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2675303 | Rat Genome Database ID: | RGD:1310115 |
HGNC ID: | HGNC:11912 | RefSeq IDs: | NM_003820 |
Entrez Gene ID: | 8764 | Ensembl Gene ID: | ENSG00000157873 |
VEGA IDs: | OTTHUMG00000000792 | UniProt ID: | Q92956 |
UCSC ID: | uc001ajt.1 | OMIM ID: | 602746 |
Pubmed: | PMID8898196 PMID 9162061 | ||
CCDS IDs: | CCDSCCDS44046.1 |
Tumor necrosis factor receptor superfamily member 14 is a protein that in humans is encoded by the TNFRSF14 gene. The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor was identified as a cellular mediator of herpes simplex virus (HSV) entry. Binding of HSV viral envelope glycoprotein D (gD) to this receptor protein has been shown to be part of the viral entry mechanism. The cytoplasmic region of this receptor was found to bind to several TRAF family members, which may mediate the signal transduction pathways that activate the immune response. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Receptor for BTLA. Receptor for TNFSF14/LIGHT and homotrimeric TNFSF1/lymphotoxin-alpha. Involved in lymphocyte activation. Plays an important role in HSV pathogenesis because it enhanced the entry of several wild-type HSV strains of both serotypes into CHO cells, and mediated HSV entry into activated human T-cells.
Products for TNFRSF14 gene
Catalog | Product Name | Application | Company |
GFS:E01723 | tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator); ELISA kit | ELISA | n/a |
GFS:A01723 | tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator); Anti | ANTIBODIES | n/a |
GFS:P01723 | tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator); Protien | Protien | n/a |