Symbol: Name: ID: |
UBE3C ubiquitin protein ligase E3C GFS:5888 |
Gene name: | UBE3C |
Chromosome: | 7q36.3 |
Previous Symbols: | |
Previous Names: | |
Aliases: | KIAA0010, KIAA10 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2140998 | Rat Genome Database ID: | RGD:1559986 |
HGNC ID: | HGNC:16803 | RefSeq IDs: | NM_014671 |
Entrez Gene ID: | 9690 | Ensembl Gene ID: | ENSG00000009335 |
VEGA IDs: | OTTHUMG00000157239 | UniProt ID: | Q15386 |
UCSC ID: | uc010lqs.2 | OMIM ID: | |
Pubmed: | PMID7584026 PMID 11278995 | ||
CCDS IDs: | CCDSCCDS34789.1 |
Ubiquitin-protein ligase E3C is an enzyme that in humans is encoded by the UBE3C gene.
Function: E3 ubiquitin-protein ligase that accepts ubiquitin from the E2 ubiquitin-conjugating enzyme UBE2D1 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Can assemble unanchored poly-ubiquitin chains in either 'Lys-29'- or 'Lys-48'-linked polyubiquitin chains. Has preference for 'Lys-48' linkages. It can target itself for ubiquitination in vitro and may promote its own degradation in vivo.
Products for UBE3C gene
Catalog | Product Name | Application | Company |
GFS:E05888 | ubiquitin protein ligase E3C; ELISA kit | ELISA | n/a |
GFS:A05888 | ubiquitin protein ligase E3C; Anti | ANTIBODIES | n/a |
GFS:P05888 | ubiquitin protein ligase E3C; Protien | Protien | n/a |