Symbol: Name: ID: |
UBE2D3 ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast) GFS:2269 |
Gene name: | UBE2D3 |
Chromosome: | 4q24 |
Previous Symbols: | |
Previous Names: | ubiquitin-conjugating enzyme E2D 3 (homologous to yeast UBC4/5) |
Aliases: | UbcH5C |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1913355 | Rat Genome Database ID: | RGD:619912 |
HGNC ID: | HGNC:12476 | RefSeq IDs: | NM_003340 |
Entrez Gene ID: | 7323 | Ensembl Gene ID: | ENSG00000109332 |
VEGA IDs: | OTTHUMG00000131119 | UniProt ID: | P61077 |
UCSC ID: | uc003hwl.2 | OMIM ID: | 602963 |
Pubmed: | PMID8530467 | ||
CCDS IDs: | CCDSCCDS3659.1 CCDS CCDS3660.1 CCDS CCDS3661.1 |
Ubiquitin-conjugating enzyme E2 D3 is a protein that in humans is encoded by the UBE2D3 gene.
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. Multiple spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq].
Products for UBE2D3 gene
Catalog | Product Name | Application | Company |
GFS:E02269 | ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast); ELISA kit | ELISA | n/a |
GFS:A02269 | ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast); Anti | ANTIBODIES | n/a |
GFS:P02269 | ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast); Protien | Protien | n/a |