Symbol: Name: ID: |
UBE2G1 ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast) GFS:2275 |
Gene name: | UBE2G1 |
Chromosome: | 17p13.2 |
Previous Symbols: | UBE2G |
Previous Names: | ubiquitin-conjugating enzyme E2G 1 (homologous to C. elegans UBC7), "ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, C. elegans)" |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1914378 | Rat Genome Database ID: | RGD:620392 |
HGNC ID: | HGNC:12482 | RefSeq IDs: | NM_003342 |
Entrez Gene ID: | 7326 | Ensembl Gene ID: | ENSG00000132388 |
VEGA IDs: | UniProt ID: | P62253 | |
UCSC ID: | uc002fxs.2 | OMIM ID: | 601569 |
Pubmed: | PMID8893823 | ||
CCDS IDs: | CCDSCCDS32532.1 |
Ubiquitin-conjugating enzyme E2 G1 is a protein that in humans is encoded by the UBE2G1 gene.
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family and catalyzes the covalent attachment of ubiquitin to other proteins. The protein may be involved in degradation of muscle-specific proteins. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-, as well as 'Lys-63'-linked polyubiquitination. May be involved in degradation of muscle-specific proteins. Mediates polyubiquitination of CYP3A4.
Products for UBE2G1 gene
Catalog | Product Name | Application | Company |
GFS:E02275 | ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast); ELISA kit | ELISA | n/a |
GFS:A02275 | ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast); Anti | ANTIBODIES | n/a |
GFS:P02275 | ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast); Protien | Protien | n/a |