Symbol: Name: ID: |
UBE2G2 ubiquitin-conjugating enzyme E2G 2 (UBC7 homolog, yeast) GFS:2276 |
Gene name: | UBE2G2 |
Chromosome: | 21q22.3 |
Previous Symbols: | |
Previous Names: | ubiquitin-conjugating enzyme E2G 2 (homologous to yeast UBC7) |
Aliases: | UBC7 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1343188 | Rat Genome Database ID: | RGD:1304860 |
HGNC ID: | HGNC:12483 | RefSeq IDs: | NM_001202489 |
Entrez Gene ID: | 7327 | Ensembl Gene ID: | ENSG00000184787 |
VEGA IDs: | OTTHUMG00000089179 | UniProt ID: | P60604 |
UCSC ID: | uc002zfy.2 | OMIM ID: | 603124 |
Pubmed: | PMID9693041 PMID 9925943 | ||
CCDS IDs: | CCDSCCDS13714.1 CCDS CCDS33586.1 |
Ubiquitin-conjugating enzyme E2 G2 is a protein that in humans is encoded by the UBE2G2 gene.
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein shares 100% sequence identity with the mouse counterpart. This gene is ubiquitously expressed, with high expression seen in adult muscle. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq].
Function: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-linked polyubiquitination. Involved in endoplasmic reticulum-associated degradation (ERAD).
Products for UBE2G2 gene
Catalog | Product Name | Application | Company |
GFS:E02276 | ubiquitin-conjugating enzyme E2G 2 (UBC7 homolog, yeast); ELISA kit | ELISA | n/a |
GFS:A02276 | ubiquitin-conjugating enzyme E2G 2 (UBC7 homolog, yeast); Anti | ANTIBODIES | n/a |
GFS:P02276 | ubiquitin-conjugating enzyme E2G 2 (UBC7 homolog, yeast); Protien | Protien | n/a |