Symbol: Name: ID: |
UBE2H ubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast) GFS:2277 |
Gene name: | UBE2H |
Chromosome: | 7q32 |
Previous Symbols: | |
Previous Names: | ubiquitin-conjugating enzyme E2H (homologous to yeast UBC8) |
Aliases: | UBCH, UBC8 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:104632 | Rat Genome Database ID: | |
HGNC ID: | HGNC:12484 | RefSeq IDs: | NM_001202498 |
Entrez Gene ID: | 7328 | Ensembl Gene ID: | ENSG00000186591 |
VEGA IDs: | OTTHUMG00000157650 | UniProt ID: | P62256 |
UCSC ID: | uc003vpe.2 | OMIM ID: | 601082 |
Pubmed: | PMID8132613 | ||
CCDS IDs: | CCDSCCDS5814.1 CCDS CCDS47710.1 |
Ubiquitin-conjugating enzyme E2 H is a protein that in humans is encoded by the UBE2H gene.
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein sequence is 100% identical to the mouse homolog and 98% identical to the frog and zebrafish homologs. Three alternatively spliced transcript variants have been found for this gene and they encode distinct isoforms. (provided by RefSeq) .
Function: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'- and 'Lys-48'-linked polyubiquitination. Capable, in vitro, to ubiquitinate histone H2A.
Products for UBE2H gene
Catalog | Product Name | Application | Company |
GFS:E02277 | ubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast); ELISA kit | ELISA | n/a |
GFS:A02277 | ubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast); Anti | ANTIBODIES | n/a |
GFS:P02277 | ubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast); Protien | Protien | n/a |