Symbol: Name: ID: |
UBE2L6 ubiquitin-conjugating enzyme E2L 6 GFS:2284 |
Gene name: | UBE2L6 |
Chromosome: | 11q12.1 |
Previous Symbols: | |
Previous Names: | |
Aliases: | UBCH8 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1914500 | Rat Genome Database ID: | RGD:1307960 |
HGNC ID: | HGNC:12490 | RefSeq IDs: | NM_004223 |
Entrez Gene ID: | 9246 | Ensembl Gene ID: | ENSG00000156587 |
VEGA IDs: | UniProt ID: | O14933 | |
UCSC ID: | uc001nkn.1 | OMIM ID: | 603890 |
Pubmed: | PMID9153201 | ||
CCDS IDs: | CCDSCCDS7960.1 CCDS CCDS7961.1 |
Ubiquitin/ISG15-conjugating enzyme E2 L6 is a protein that in humans is encoded by the UBE2L6 gene.
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is highly similar in primary structure to the enzyme encoded by the UBE2L3 gene. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq].
Function: Catalyzes the covalent attachment of ubiquitin or ISG15 to other proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53.
Products for UBE2L6 gene
Catalog | Product Name | Application | Company |
GFS:E02284 | ubiquitin-conjugating enzyme E2L 6; ELISA kit | ELISA | n/a |
GFS:A02284 | ubiquitin-conjugating enzyme E2L 6; Anti | ANTIBODIES | n/a |
GFS:P02284 | ubiquitin-conjugating enzyme E2L 6; Protien | Protien | n/a |