Symbol: Name: ID: |
UBE2E1 ubiquitin-conjugating enzyme E2E 1 (UBC4/5 homolog, yeast) GFS:2270 |
Gene name: | UBE2E1 |
Chromosome: | 3p24.2 |
Previous Symbols: | |
Previous Names: | ubiquitin-conjugating enzyme E2E 1 (homologous to yeast UBC4/5) |
Aliases: | UbcH6 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:107411 | Rat Genome Database ID: | |
HGNC ID: | HGNC:12477 | RefSeq IDs: | NM_001202476 |
Entrez Gene ID: | 7324 | Ensembl Gene ID: | ENSG00000170142 |
VEGA IDs: | OTTHUMG00000130483 | UniProt ID: | P51965 |
UCSC ID: | uc003cch.2 | OMIM ID: | 602916 |
Pubmed: | PMID8576257 | ||
CCDS IDs: | CCDSCCDS2638.1 CCDS CCDS2639.1 |
Ubiquitin-conjugating enzyme E2 E1 is a protein that in humans is encoded by the UBE2E1 gene.
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq].
Function: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Catalyzes the covalent attachment of ISG15 to other proteins. Mediates the selective degradation of short-lived and abnormal proteins. In vitro also catalyzes 'Lys-48'-linked polyubiquitination.
Products for UBE2E1 gene
Catalog | Product Name | Application | Company |
GFS:E02270 | ubiquitin-conjugating enzyme E2E 1 (UBC4/5 homolog, yeast); ELISA kit | ELISA | n/a |
GFS:A02270 | ubiquitin-conjugating enzyme E2E 1 (UBC4/5 homolog, yeast); Anti | ANTIBODIES | n/a |
GFS:P02270 | ubiquitin-conjugating enzyme E2E 1 (UBC4/5 homolog, yeast); Protien | Protien | n/a |