Symbol: Name: ID: |
UBE3B ubiquitin protein ligase E3B GFS:3041 |
Gene name: | UBE3B |
Chromosome: | 12q24.12 |
Previous Symbols: | |
Previous Names: | |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1891295 | Rat Genome Database ID: | RGD:1583074 |
HGNC ID: | HGNC:13478 | RefSeq IDs: | NM_130466 |
Entrez Gene ID: | 89910 | Ensembl Gene ID: | ENSG00000151148 |
VEGA IDs: | UniProt ID: | Q7Z3V4 | |
UCSC ID: | uc001toq.2 | OMIM ID: | 608047 |
Pubmed: | |||
CCDS IDs: | CCDSCCDS9129.1 |
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E3 ubiquitin-conjugating enzyme family. The encoded protein may interact with other proteins and play a role in stress response. Alternatively spliced transcript variants encoding the same protein isoform have been identified for this gene. [provided by RefSeq, Jul 2008].
Function: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates (By similarity).
Products for UBE3B gene
Catalog | Product Name | Application | Company |
GFS:E03041 | ubiquitin protein ligase E3B; ELISA kit | ELISA | n/a |
GFS:A03041 | ubiquitin protein ligase E3B; Anti | ANTIBODIES | n/a |
GFS:P03041 | ubiquitin protein ligase E3B; Protien | Protien | n/a |