Symbol: Name: ID: |
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa GFS:6390 |
Gene name: | TAF5L |
Chromosome: | 1q42.11-q42.3 |
Previous Symbols: | |
Previous Names: | TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65 kD |
Aliases: | PAF65B |
Name Aliases: | PCAF associated factor 65 beta |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1919039 | Rat Genome Database ID: | RGD:1310215 |
HGNC ID: | HGNC:17304 | RefSeq IDs: | NM_001025247 |
Entrez Gene ID: | 27097 | Ensembl Gene ID: | ENSG00000135801 |
VEGA IDs: | OTTHUMG00000039463 | UniProt ID: | O75529 |
UCSC ID: | uc001htq.2 | OMIM ID: | |
Pubmed: | PMID9674425 PMID 11124703 | ||
CCDS IDs: | CCDSCCDS1581.1 CCDS CCDS31051.1 |
TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L is an enzyme that in humans is encoded by the TAF5L gene.
The product of this gene belongs to the WD-repeat TAF5 family of proteins. This gene encodes a protein that is a component of the PCAF histone acetylase complex. The PCAF histone acetylase complex, which is composed of more than 20 polypeptides some of which are TAFs, is required for myogenic transcription and differentiation. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors to facilitate complex assembly and transcription initiation. The encoded protein is structurally similar to one of the histone-like TAFs, TAF5. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008].
Function: Functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex could be considered as the human version of the yeast SAGA complex.
Products for TAF5L gene
Catalog | Product Name | Application | Company |
GFS:E06390 | TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa; ELISA kit | ELISA | n/a |
GFS:A06390 | TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa; Anti | ANTIBODIES | n/a |
GFS:P06390 | TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa; Protien | Protien | n/a |