Symbol: Name: ID: |
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa GFS:1395 |
Gene name: | TAF4B |
Chromosome: | 18q11.1 |
Previous Symbols: | TAF2C2 |
Previous Names: | TATA box binding protein (TBP)-associated factor, RNA polymerase II, C2, 105kD |
Aliases: | TAFII105 |
Name Aliases: | TATA box binding protein (TBP)-associated factor 4B |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2152345 | Rat Genome Database ID: | |
HGNC ID: | HGNC:11538 | RefSeq IDs: | NM_005640 |
Entrez Gene ID: | 6875 | Ensembl Gene ID: | ENSG00000141384 |
VEGA IDs: | UniProt ID: | Q92750 | |
UCSC ID: | uc002kvu.3 | OMIM ID: | 601689 |
Pubmed: | PMID8858156 PMID 10849440 | ||
CCDS IDs: | CCDSCCDS42421.1 |
Transcription initiation factor TFIID subunit 4B is a protein that in humans is encoded by the TAF4B gene. TATA-binding protein associated factors (TAFs) participate, with TATA binding protein (TBP; MIM 600075), in the formation of the TFIID protein complex (see MIM 313650), which is involved in the initiation of gene transcription by RNA polymerase II (see MIM 180660).(supplied by OMIM)
Cell type-specific subunit of TFIID that may function as a gene-selective coactivator in certain cells. TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. TAFII105 is a transcriptional coactivator of the p65/RELA NF-kappa-B subunit. Involved in the activation of a subset of antiapoptotic genes including TNFAIP3. May be involved in regulating folliculogenesis. Through interaction with OCBA/POU2AF1, acts as a coactivator of B cell-specific transcription.
Products for TAF4B gene
Catalog | Product Name | Application | Company |
GFS:E01395 | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa; ELISA kit | ELISA | n/a |
GFS:A01395 | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa; Anti | ANTIBODIES | n/a |
GFS:P01395 | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa; Protien | Protien | n/a |