Symbol: Name: ID: |
CDK2AP1 cyclin-dependent kinase 2 associated protein 1 GFS:3437 |
Gene name: | CDK2AP1 |
Chromosome: | 12q24 |
Previous Symbols: | |
Previous Names: | CDK2-associated protein 1 |
Aliases: | DORC1, doc-1, DOC1, ST19, p12DOC-1 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1202069 | Rat Genome Database ID: | RGD:1308664 |
HGNC ID: | HGNC:14002 | RefSeq IDs: | NM_004642 |
Entrez Gene ID: | 8099 | Ensembl Gene ID: | ENSG00000111328 |
VEGA IDs: | UniProt ID: | O14519 | |
UCSC ID: | uc001ueq.2 | OMIM ID: | 602198 |
Pubmed: | PMID9331572 PMID 9506968 | ||
CCDS IDs: | CCDSCCDS9245.1 |
Cyclin-dependent kinase 2-associated protein 1 is an enzyme that in humans is encoded by the CDK2AP1 gene.
The protein encoded by this gene is a specific CDK2-associated protein, which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. This protein was found to also interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggested the regulatory role in DNA replication during S phase of the cell cycle. A similar gene in hamster was isolated from, and functions as a growth suppressor of normal keratinocytes. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Products for CDK2AP1 gene
Catalog | Product Name | Application | Company |
GFS:E03437 | cyclin-dependent kinase 2 associated protein 1; ELISA kit | ELISA | n/a |
GFS:A03437 | cyclin-dependent kinase 2 associated protein 1; Anti | ANTIBODIES | n/a |
GFS:P03437 | cyclin-dependent kinase 2 associated protein 1; Protien | Protien | n/a |