Symbol: Name: ID: |
CDK2 cyclin-dependent kinase 2 GFS:6637 |
Gene name: | CDK2 |
Chromosome: | 12q13 |
Previous Symbols: | |
Previous Names: | |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:104772 | Rat Genome Database ID: | RGD:70486 |
HGNC ID: | HGNC:1771 | RefSeq IDs: | NM_001798 |
Entrez Gene ID: | 1017 | Ensembl Gene ID: | ENSG00000123374 |
VEGA IDs: | UniProt ID: | P24941 | |
UCSC ID: | uc001sit.3 | OMIM ID: | 116953 |
Pubmed: | PMID1717994 PMID 8275715 | ||
CCDS IDs: | CCDSCCDS8898.1 CCDS CCDS8899.1 |
Cyclin-dependent kinase 2 also known as cell division protein kinase 2 is an enzyme that in humans is encoded by the CDK2 gene.
The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. This protein associates with and regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by its protein phosphorylation. Two alternatively spliced variants and multiple transcription initiation sites of this gene have been reported. [provided by RefSeq, Jul 2008].
Function: Involved in the control of the cell cycle. Interacts with cyclins A, B1, B3, D, or E. Activity of CDK2 is maximal during S phase and G2.
Products for CDK2 gene
Catalog | Product Name | Application | Company |
GFS:E06637 | cyclin-dependent kinase 2; ELISA kit | ELISA | n/a |
GFS:A06637 | cyclin-dependent kinase 2; Anti | ANTIBODIES | n/a |
GFS:P06637 | cyclin-dependent kinase 2; Protien | Protien | n/a |