Symbol: Name: ID: |
NFS1 NFS1 nitrogen fixation 1 homolog (S. cerevisiae) GFS:5044 |
Gene name: | NFS1 |
Chromosome: | 20q11.22 |
Previous Symbols: | |
Previous Names: | nitrogen fixation 1 (S. cerevisiae, homolog) |
Aliases: | NifS, IscS |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1316706 | Rat Genome Database ID: | RGD:620912 |
HGNC ID: | HGNC:15910 | RefSeq IDs: | NM_001198989 |
Entrez Gene ID: | 9054 | Ensembl Gene ID: | ENSG00000244005 |
VEGA IDs: | OTTHUMG00000032361 | UniProt ID: | Q9Y697 |
UCSC ID: | uc002xdw.1 | OMIM ID: | 603485 |
Pubmed: | PMID9885568 PMID 16847322 | ||
CCDS IDs: | CCDSCCDS13262.1 |
Cysteine desulfurase, mitochondrial is an enzyme that in humans is encoded by the NFS1 gene.
Iron-sulfur clusters are required for the function of many cellular enzymes. The proteins encoded by this gene supply inorganic sulfur to these clusters by removing the sulfur from cysteine, creating alanine in the process. This gene uses alternate in-frame translation initiation sites to generate mitochondrial forms and cytoplasmic/nuclear forms. Selection of the alternative initiation sites is determined by the cytosolic pH. The encoded proteins belong to the class-V family of pyridoxal phosphate-dependent aminotransferases. Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2010].
Function: Catalyzes the removal of elemental sulfur from cysteine to produce alanine. It supplies the inorganic sulfur for iron-sulfur (Fe-S) clusters. May be involved in the biosynthesis of molybdenum cofactor.
Products for NFS1 gene
Catalog | Product Name | Application | Company |
GFS:E05044 | NFS1 nitrogen fixation 1 homolog (S. cerevisiae); ELISA kit | ELISA | n/a |
GFS:A05044 | NFS1 nitrogen fixation 1 homolog (S. cerevisiae); Anti | ANTIBODIES | n/a |
GFS:P05044 | NFS1 nitrogen fixation 1 homolog (S. cerevisiae); Protien | Protien | n/a |