Symbol: Name: ID: |
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 GFS:1746 |
Gene name: | TNFSF4 |
Chromosome: | 1q25 |
Previous Symbols: | TXGP1 |
Previous Names: | tax-transcriptionally activated glycoprotein 1, 34kD |
Aliases: | OX-40L, gp34, CD252 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:104511 | Rat Genome Database ID: | RGD:619816 |
HGNC ID: | HGNC:11934 | RefSeq IDs: | NM_003326 |
Entrez Gene ID: | 7292 | Ensembl Gene ID: | ENSG00000117586 |
VEGA IDs: | OTTHUMG00000034838 | UniProt ID: | P23510 |
UCSC ID: | uc001giw.2 | OMIM ID: | 603594 |
Pubmed: | PMID1996093 PMID 8076595 | ||
CCDS IDs: | CCDSCCDS1306.1 |
The protein encoded by TNFSF4 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF4/OX4. It is found to be involved in T cell antigen-presenting cell (APC) interactions. In surface Ig- and CD40-stimulated B cells, this cytokine along with CD70 has been shown to provide CD28-independent costimulatory signals to T cells. This protein and its receptor are reported to directly mediate adhesion of activated T cells to vascular endothelial cells. [provided by RefSeq]. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Cytokine that binds to TNFRSF4. Co-stimulates T-cell proliferation and cytokine production.
Products for TNFSF4 gene
Catalog | Product Name | Application | Company |
GFS:E01746 | tumor necrosis factor (ligand) superfamily, member 4; ELISA kit | ELISA | n/a |
GFS:A01746 | tumor necrosis factor (ligand) superfamily, member 4; Anti | ANTIBODIES | n/a |
GFS:P01746 | tumor necrosis factor (ligand) superfamily, member 4; Protien | Protien | n/a |