Symbol: Name: ID: |
FBXO7 F-box protein 7 GFS:3129 |
Gene name: | FBXO7 |
Chromosome: | 22q11.2-qter |
Previous Symbols: | |
Previous Names: | F-box only protein 7 |
Aliases: | FBX7, Fbx, PARK15 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1917004 | Rat Genome Database ID: | RGD:1305648 |
HGNC ID: | HGNC:13586 | RefSeq IDs: | NM_001033024 |
Entrez Gene ID: | 25793 | Ensembl Gene ID: | ENSG00000100225 |
VEGA IDs: | OTTHUMG00000030674 | UniProt ID: | Q9Y3I1 |
UCSC ID: | uc003amq.2 | OMIM ID: | 605648 |
Pubmed: | PMID10531035 PMID 10531037 PMID 19038853 | ||
CCDS IDs: | CCDSCCDS13907.1 CCDS CCDS46695.1 |
F-box only protein 7 is a protein that in humans is encoded by the FBXO7 gene.
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it may play a role in regulation of hematopoiesis. Alternatively spliced transcript variants of this gene have been identified with the full-length natures of only some variants being determined. [provided by RefSeq, Jul 2008].
Function: Substrate recognition component of a (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes BIRC2 and DLGAP5.
Products for FBXO7 gene
Catalog | Product Name | Application | Company |
GFS:E03129 | F-box protein 7; ELISA kit | ELISA | n/a |
GFS:A03129 | F-box protein 7; Anti | ANTIBODIES | n/a |
GFS:P03129 | F-box protein 7; Protien | Protien | n/a |