Symbol: Name: ID: |
FBXO25 F-box protein 25 GFS:3139 |
Gene name: | FBXO25 |
Chromosome: | 8p23.3 |
Previous Symbols: | |
Previous Names: | F-box only protein 25 |
Aliases: | FBX25 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1914072 | Rat Genome Database ID: | RGD:1359105 |
HGNC ID: | HGNC:13596 | RefSeq IDs: | NM_012173 |
Entrez Gene ID: | 26260 | Ensembl Gene ID: | ENSG00000147364 |
VEGA IDs: | OTTHUMG00000090341 | UniProt ID: | Q8TCJ0 |
UCSC ID: | uc003wox.2 | OMIM ID: | 609098 |
Pubmed: | PMID10531035 PMID 10531037 | ||
CCDS IDs: | CCDSCCDS5952.1 CCDS CCDS5953.1 CCDS CCDS5954.1 |
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Function: Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. May play a role in accumulation of expanded polyglutamine (polyQ) protein huntingtin (HTT) (By similarity).
Products for FBXO25 gene
Catalog | Product Name | Application | Company |
GFS:E03139 | F-box protein 25; ELISA kit | ELISA | n/a |
GFS:A03139 | F-box protein 25; Anti | ANTIBODIES | n/a |
GFS:P03139 | F-box protein 25; Protien | Protien | n/a |