| Symbol: Name: ID: |
FBXO27 F-box protein 27 GFS:7589 |
| Gene name: | FBXO27 |
| Chromosome: | 19q13.2 |
| Previous Symbols: | |
| Previous Names: | F-box only protein 27 |
| Aliases: | Fbg5, Fbx27 |
| Name Aliases: | |
| Locus Type: | gene with protein product |
| Mouse Genome Database ID: | MGI:2685007 | Rat Genome Database ID: | |
| HGNC ID: | HGNC:18753 | RefSeq IDs: | NM_178820 |
| Entrez Gene ID: | 126433 | Ensembl Gene ID: | ENSG00000161243 |
| VEGA IDs: | UniProt ID: | Q8NI29 | |
| UCSC ID: | uc002okh.2 | OMIM ID: | 609099 |
| Pubmed: | PMID126433 | ||
| CCDS IDs: | CCDSCCDS12527.1 | ||
Members of the F-box protein family, such as FBXO27, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008].
Function: Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Able to recognize and bind denatured glycoproteins, which are modified with complex-type oligosaccharides.
Products for FBXO27 gene
| Catalog | Product Name | Application | Company |
| GFS:E07589 | F-box protein 27; ELISA kit | ELISA | n/a |
| GFS:A07589 | F-box protein 27; Anti | ANTIBODIES | n/a |
| GFS:P07589 | F-box protein 27; Protien | Protien | n/a |
