Symbol: Name: ID: |
TAT tyrosine aminotransferase GFS:1425 |
Gene name: | TAT |
Chromosome: | 16q22.1 |
Previous Symbols: | |
Previous Names: | |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:98487 | Rat Genome Database ID: | RGD:3820 |
HGNC ID: | HGNC:11573 | RefSeq IDs: | NM_000353 |
Entrez Gene ID: | 6898 | Ensembl Gene ID: | ENSG00000198650 |
VEGA IDs: | OTTHUMG00000137590 | UniProt ID: | P17735 |
UCSC ID: | uc002fap.2 | OMIM ID: | 613018 |
Pubmed: | |||
CCDS IDs: | CCDSCCDS10903.1 |
This nuclear gene encodes a mitochondrial protein tyrosine aminotransferase which is present in the liver and catalyzes the conversion of L-tyrosine into p-hydroxyphenylpyruvate. Mutations in this gene cause tyrosinemia (type II, Richner-Hanhart syndrome), a disorder accompanied by major skin and corneal lesions, with possible mental retardation. A regulator gene for tyrosine aminotransferase is X-linked. [provided by RefSeq]. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. Can catalyze the reverse reaction, using glutamic acid, with 2-oxoglutarate as cosubstrate (in vitro). Has no transaminase activity towards phenylalanine.
Products for TAT gene
Catalog | Product Name | Application | Company |
GFS:E01425 | tyrosine aminotransferase; ELISA kit | ELISA | n/a |
GFS:A01425 | tyrosine aminotransferase; Anti | ANTIBODIES | n/a |
GFS:P01425 | tyrosine aminotransferase; Protien | Protien | n/a |