Symbol: Name: ID: |
STAT1 signal transducer and activator of transcription 1, 91kDa GFS:1252 |
Gene name: | STAT1 |
Chromosome: | 2q32.2-q32.3 |
Previous Symbols: | |
Previous Names: | signal transducer and activator of transcription 1, 91kD |
Aliases: | STAT91, ISGF-3 |
Name Aliases: | transcription factor ISGF-3 components p91/p84 |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:103063 | Rat Genome Database ID: | RGD:3771 |
HGNC ID: | HGNC:11362 | RefSeq IDs: | NM_007315 |
Entrez Gene ID: | 6772 | Ensembl Gene ID: | |
VEGA IDs: | OTTHUMG00000132699 | UniProt ID: | P42224 |
UCSC ID: | uc002usj.2 | OMIM ID: | 600555 |
Pubmed: | PMID7885841 | ||
CCDS IDs: | CCDSCCDS2309.1 CCDS CCDS42793.1 |
STAT1 is a member of the Signal Transducers and Activators of Transcription family of transcription factors. The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq].
Products for STAT1 gene
Catalog | Product Name | Application | Company |
GFS:E01252 | signal transducer and activator of transcription 1, 91kDa; ELISA kit | ELISA | n/a |
GFS:A01252 | signal transducer and activator of transcription 1, 91kDa; Anti | ANTIBODIES | n/a |
GFS:P01252 | signal transducer and activator of transcription 1, 91kDa; Protien | Protien | n/a |