Symbol: Name: ID: |
TCF20 transcription factor 20 (AR1) GFS:1478 |
Gene name: | TCF20 |
Chromosome: | 22q13.3 |
Previous Symbols: | |
Previous Names: | |
Aliases: | AR1, SPBP |
Name Aliases: | stromelysin-1 platelet-derived growth factor-responsive element binding protein |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:108399 | Rat Genome Database ID: | RGD:1594486 |
HGNC ID: | HGNC:11631 | RefSeq IDs: | NM_005650 |
Entrez Gene ID: | 6942 | Ensembl Gene ID: | ENSG00000100207 |
VEGA IDs: | OTTHUMG00000150920 | UniProt ID: | Q9UGU0 |
UCSC ID: | uc003bcj.1 | OMIM ID: | 603107 |
Pubmed: | PMID9730594 PMID 10995766 | ||
CCDS IDs: | CCDSCCDS14032.1 CCDS CCDS14033.1 |
Transcription factor 20 is a protein that in humans is encoded by the TCF20 gene. The protein encoded by this gene binds a platelet-derived growth factor-responsive element in the matrix metalloproteinase 3 (stromelysin 1) promoter. The protein localizes to the nucleus and displays DNA-binding and transactivation activities. It is thought to be a transcriptional coactivator, enhancing the activity of transcription factors such as JUN and SP1. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq].
Transcriptional activator that binds to the regulatory region of MMP3 and thereby controls stromelysin expression. It stimulates the activity of various transcriptional activators such as JUN, SP1, PAX6 and ETS1, suggesting a function as a coactivator.
Products for TCF20 gene
Catalog | Product Name | Application | Company |
GFS:E01478 | transcription factor 20 (AR1); ELISA kit | ELISA | n/a |
GFS:A01478 | transcription factor 20 (AR1); Anti | ANTIBODIES | n/a |
GFS:P01478 | transcription factor 20 (AR1); Protien | Protien | n/a |