Symbol: Name: ID: |
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1 GFS:3424 |
Gene name: | CACNA2D1 |
Chromosome: | 7q21-q22 |
Previous Symbols: | CACNL2A, CACNA2, MHS3 |
Previous Names: | |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:88295 | Rat Genome Database ID: | RGD:2247 |
HGNC ID: | HGNC:1399 | RefSeq IDs: | NM_000722 |
Entrez Gene ID: | 781 | Ensembl Gene ID: | ENSG00000153956 |
VEGA IDs: | OTTHUMG00000023622 | UniProt ID: | P54289 |
UCSC ID: | uc003uhr.1 | OMIM ID: | 114204 |
Pubmed: | PMID8188232 | ||
CCDS IDs: | CCDSCCDS5598.1 |
Voltage-dependent calcium channel subunit alpha-2/delta-1 is a protein that in humans is encoded by the CACNA2D1 gene.
This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel. Plays an important role in excitation-contraction coupling (By similarity).
Products for CACNA2D1 gene
Catalog | Product Name | Application | Company |
GFS:E03424 | calcium channel, voltage-dependent, alpha 2/delta subunit 1; ELISA kit | ELISA | n/a |
GFS:A03424 | calcium channel, voltage-dependent, alpha 2/delta subunit 1; Anti | ANTIBODIES | n/a |
GFS:P03424 | calcium channel, voltage-dependent, alpha 2/delta subunit 1; Protien | Protien | n/a |