Symbol: Name: ID: |
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit GFS:3347 |
Gene name: | CACNA1C |
Chromosome: | 12p13.3 |
Previous Symbols: | CCHL1A1, CACNL1A1 |
Previous Names: | |
Aliases: | Cav1.2, CACH2, CACN2, TS |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:103013 | Rat Genome Database ID: | RGD:2245 |
HGNC ID: | HGNC:1390 | RefSeq IDs: | NM_000719 |
Entrez Gene ID: | 775 | Ensembl Gene ID: | ENSG00000151067 |
VEGA IDs: | OTTHUMG00000150243 | UniProt ID: | Q13936 |
UCSC ID: | uc001qjy.2 | OMIM ID: | 114205 |
Pubmed: | PMID1650913 PMID 16382099 | ||
CCDS IDs: | CCDSCCDS44787.1 CCDS CCDS44788.1 CCDS CCDS44789.1 CCDS CCDS44790.1 CCDS CCDS44791.1 CCDS CCDS44792.1 CCDS CCDS44793.1 CCDS CCDS44794.1 CCDS CCDS44795.1 CCDS CCDS44796.1 CCDS CCDS44797.1 CCDS CCDS44798.1 CCDS CCDS44799.1 CCDS CCDS44800.1 CCDS CCDS44801.1 |
Calcium channel, voltage-dependent, L type, alpha 1C subunit (also known as Cav1.2) is a protein that in humans is encoded by the CACNA1C gene. Cav1.2 is a subunit of L-type voltage-dependent calcium channel.
This gene encodes an alpha-1 subunit of a voltage-dependent calcium channel. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. There are multiple isoforms of each of these proteins, either encoded by different genes or the result of alternative splicing of transcripts. The protein encoded by this gene binds to and is inhibited by dihydropyridine. Alternative splicing results in many transcript variants encoding different proteins. (provided by RefSeq) .
Products for CACNA1C gene
Catalog | Product Name | Application | Company |
GFS:E03347 | calcium channel, voltage-dependent, L type, alpha 1C subunit; ELISA kit | ELISA | n/a |
GFS:A03347 | calcium channel, voltage-dependent, L type, alpha 1C subunit; Anti | ANTIBODIES | n/a |
GFS:P03347 | calcium channel, voltage-dependent, L type, alpha 1C subunit; Protien | Protien | n/a |