Symbol: Name: ID: |
SP2 Sp2 transcription factor GFS:1108 |
Gene name: | SP2 |
Chromosome: | 17q21.3-q22 |
Previous Symbols: | |
Previous Names: | |
Aliases: | KIAA0048 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1926162 | Rat Genome Database ID: | RGD:1592078 |
HGNC ID: | HGNC:11207 | RefSeq IDs: | NM_003110 |
Entrez Gene ID: | 6668 | Ensembl Gene ID: | ENSG00000167182 |
VEGA IDs: | OTTHUMG00000150196 | UniProt ID: | Q02086 |
UCSC ID: | uc002imk.2 | OMIM ID: | 601801 |
Pubmed: | PMID1341900 PMID 9730617 | ||
CCDS IDs: | CCDSCCDS11521.2 |
Transcription factor Sp2 is a protein that in humans is encoded by the SP2 gene. This gene encodes a member of the Sp subfamily of Sp/XKLF transcription factors. Sp family proteins are sequence-specific DNA-binding proteins characterized by an amino-terminal trans-activation domain and three carboxy-terminal zinc finger motifs. This protein contains the least conserved DNA-binding domain within the Sp subfamily of proteins, and its DNA sequence specificity differs from the other Sp proteins. It localizes primarily within subnuclear foci associated with the nuclear matrix, and can activate or in some cases repress expression from different promoters. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Binds to GC box promoters elements and selectively activates mRNA synthesis from genes that contain functional recognition sites.
Products for SP2 gene
Catalog | Product Name | Application | Company |
GFS:E01108 | Sp2 transcription factor; ELISA kit | ELISA | n/a |
GFS:A01108 | Sp2 transcription factor; Anti | ANTIBODIES | n/a |
GFS:P01108 | Sp2 transcription factor; Protien | Protien | n/a |