Symbol: Name: ID: |
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta GFS:3008 |
Gene name: | PPP2R3B |
Chromosome: | Xp22.3 and Yp11.3 |
Previous Symbols: | PPP2R3L |
Previous Names: | protein phosphatase 2 (formerly 2A), regulatory subunit B'', beta |
Aliases: | PPP2R3LY |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | Rat Genome Database ID: | ||
HGNC ID: | HGNC:13417 | RefSeq IDs: | NM_013239 |
Entrez Gene ID: | 28227 | Ensembl Gene ID: | ENSG00000167393 |
VEGA IDs: | OTTHUMG00000021052 | UniProt ID: | Q9Y5P8 |
UCSC ID: | uc004cpg.2 | OMIM ID: | 300339 |
Pubmed: | PMID11173861 | ||
CCDS IDs: | CCDSCCDS14104.1 |
Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta is an enzyme that in humans is encoded by the PPP2R3B gene.
Protein phosphatase 2 (formerly named type 2A) is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2 holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B'' family. The B'' family has been further divided into subfamilies. The product of this gene belongs to the beta subfamily of regulatory subunit B''. [provided by RefSeq]. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.
Function: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.
Products for PPP2R3B gene
Catalog | Product Name | Application | Company |
GFS:E03008 | protein phosphatase 2, regulatory subunit B'', beta; ELISA kit | ELISA | n/a |
GFS:A03008 | protein phosphatase 2, regulatory subunit B'', beta; Anti | ANTIBODIES | n/a |
GFS:P03008 | protein phosphatase 2, regulatory subunit B'', beta; Protien | Protien | n/a |