Symbol: Name: ID: |
PPP1R14C protein phosphatase 1, regulatory (inhibitor) subunit 14C GFS:4235 |
Gene name: | PPP1R14C |
Chromosome: | 6q24.3-q25.3 |
Previous Symbols: | |
Previous Names: | |
Aliases: | CPI17-like, NY-BR-81, KEPI |
Name Aliases: | kinase C-enhanced PP1 inhibitor |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1923392 | Rat Genome Database ID: | RGD:620538 |
HGNC ID: | HGNC:14952 | RefSeq IDs: | NM_030949 |
Entrez Gene ID: | 81706 | Ensembl Gene ID: | ENSG00000198729 |
VEGA IDs: | OTTHUMG00000015818 | UniProt ID: | Q8TAE6 |
UCSC ID: | uc003qnt.2 | OMIM ID: | 613242 |
Pubmed: | PMID11948623 | ||
CCDS IDs: | CCDSCCDS5226.1 |
Protein phosphatase 1 regulatory subunit 14C is an enzyme that in humans is encoded by the PPP1R14C gene.
The degree of protein phosphorylation is regulated by a balance of protein kinase and phosphatase activities. Protein phosphatase-1 (PP1; see MIM 176875) is a signal-transducing phosphatase that influences neuronal activity, protein synthesis, metabolism, muscle contraction, and cell division. PPP1R14C is an inhibitor of PP1 (Liu et al., 2002 [PubMed 11812771]).[supplied by OMIM, Feb 2010].
Function: Inhibitor of PPP1CA. Has over 600-fold higher inhibitory activity when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction (By similarity).
Products for PPP1R14C gene
Catalog | Product Name | Application | Company |
GFS:E04235 | protein phosphatase 1, regulatory (inhibitor) subunit 14C; ELISA kit | ELISA | n/a |
GFS:A04235 | protein phosphatase 1, regulatory (inhibitor) subunit 14C; Anti | ANTIBODIES | n/a |
GFS:P04235 | protein phosphatase 1, regulatory (inhibitor) subunit 14C; Protien | Protien | n/a |