| Symbol: Name: ID: |
PPP1R13L protein phosphatase 1, regulatory (inhibitor) subunit 13 like GFS:7655 |
| Gene name: | PPP1R13L |
| Chromosome: | 19q13.32 |
| Previous Symbols: | |
| Previous Names: | |
| Aliases: | RAI, IASPP |
| Name Aliases: | |
| Locus Type: | gene with protein product |
| Mouse Genome Database ID: | MGI:3525053 | Rat Genome Database ID: | |
| HGNC ID: | HGNC:18838 | RefSeq IDs: | NM_001142502 |
| Entrez Gene ID: | 10848 | Ensembl Gene ID: | ENSG00000104881 |
| VEGA IDs: | OTTHUMG00000071659 | UniProt ID: | Q8WUF5 |
| UCSC ID: | uc002pbn.2 | OMIM ID: | 607463 |
| Pubmed: | PMID10336463 | ||
| CCDS IDs: | CCDSCCDS33050.1 | ||
RelA-associated inhibitor is a protein that in humans is encoded by the PPP1R13L gene.
IASPP is one of the most evolutionarily conserved inhibitors of p53 (TP53; MIM 191170), whereas ASPP1 (MIM 606455) and ASPP2 (MIM 602143) are activators of p53.[supplied by OMIM, Mar 2008].
Function: Regulator that plays a central role in regulation of apoptosis and transcription via its interaction with NF-kappa-B and p53/TP53 proteins. Blocks transcription of HIV-1 virus by inhibiting the action of both NF-kappa-B and SP1. Also inhibits p53/TP53 function, possibly by preventing the association between p53/TP53 and ASPP1 or ASPP2, and therefore suppressing the subsequent activation of apoptosis.
Products for PPP1R13L gene
| Catalog | Product Name | Application | Company |
| GFS:E07655 | protein phosphatase 1, regulatory (inhibitor) subunit 13 like; ELISA kit | ELISA | n/a |
| GFS:A07655 | protein phosphatase 1, regulatory (inhibitor) subunit 13 like; Anti | ANTIBODIES | n/a |
| GFS:P07655 | protein phosphatase 1, regulatory (inhibitor) subunit 13 like; Protien | Protien | n/a |
