| Symbol: Name: ID: |
COL25A1 collagen, type XXV, alpha 1 GFS:7450 |
| Gene name: | COL25A1 |
| Chromosome: | 4q25 |
| Previous Symbols: | |
| Previous Names: | |
| Aliases: | |
| Name Aliases: | |
| Locus Type: | gene with protein product |
| Mouse Genome Database ID: | MGI:1924268 | Rat Genome Database ID: | |
| HGNC ID: | HGNC:18603 | RefSeq IDs: | NM_032518 |
| Entrez Gene ID: | 84570 | Ensembl Gene ID: | ENSG00000188517 |
| VEGA IDs: | OTTHUMG00000150039 | UniProt ID: | Q9BXS0 |
| UCSC ID: | uc003hze.1 | OMIM ID: | 610004 |
| Pubmed: | PMID11927537 | ||
| CCDS IDs: | CCDSCCDS43258.1 CCDS CCDS43259.1 | ||
Collagen alpha-1(XXV) chain is a protein that in humans is encoded by the COL25A1 gene.
COL25A1 is a brain-specific membrane-bound collagen. Proteolytic processing releases CLAC, a soluble form of COL25A1 containing the extracellular collagen domains that associates with senile plaques in Alzheimer disease (AD; MIM 104300) brains (Osada et al., 2005 [PubMed 15615705]).[supplied by OMIM, Mar 2008].
Function: Inhibits fibrillization of beta amyloid peptide during the elongation phase. Has also been shown to assemble amyloid fibrils into protease-resistant aggregates. Binds heparin.
Products for COL25A1 gene
| Catalog | Product Name | Application | Company |
| GFS:E07450 | collagen, type XXV, alpha 1; ELISA kit | ELISA | n/a |
| GFS:A07450 | collagen, type XXV, alpha 1; Anti | ANTIBODIES | n/a |
| GFS:P07450 | collagen, type XXV, alpha 1; Protien | Protien | n/a |
