Symbol: Name: ID: |
COL5A3 collagen, type V, alpha 3 GFS:4151 |
Gene name: | COL5A3 |
Chromosome: | 19p13.2 |
Previous Symbols: | |
Previous Names: | |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1858212 | Rat Genome Database ID: | RGD:70922 |
HGNC ID: | HGNC:14864 | RefSeq IDs: | NM_015719 |
Entrez Gene ID: | 50509 | Ensembl Gene ID: | ENSG00000080573 |
VEGA IDs: | OTTHUMG00000150019 | UniProt ID: | P25940 |
UCSC ID: | uc002mmq.1 | OMIM ID: | 120216 |
Pubmed: | PMID10722718 | ||
CCDS IDs: | CCDSCCDS12222.1 |
Collagen alpha-3(V) chain is a protein that in humans is encoded by the COL5A3 gene.
This gene encodes an alpha chain for one of the low abundance fibrillar collagens. Fibrillar collagen molecules are trimers that can be composed of one or more types of alpha chains. Type V collagen is found in tissues containing type I collagen and appears to regulate the assembly of heterotypic fibers composed of both type I and type V collagen. This gene product is closely related to type XI collagen and it is possible that the collagen chains of types V and XI constitute a single collagen type with tissue-specific chain combinations. Mutations in this gene are thought to be responsible for the symptoms of a subset of patients with Ehlers-Danlos syndrome type III. Messages of several sizes can be detected in northern blots but sequence information cannot confirm the identity of the shorter messages. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Type V collagen is a member of group I collagen (fibrillar forming collagen). It is a minor connective tissue component of nearly ubiquitous distribution. Type V collagen binds to DNA, heparan sulfate, thrombospondin, heparin, and insulin.
Products for COL5A3 gene
Catalog | Product Name | Application | Company |
GFS:E04151 | collagen, type V, alpha 3; ELISA kit | ELISA | n/a |
GFS:A04151 | collagen, type V, alpha 3; Anti | ANTIBODIES | n/a |
GFS:P04151 | collagen, type V, alpha 3; Protien | Protien | n/a |