Symbol: Name: ID: |
CHD5 chromodomain helicase DNA binding protein 5 GFS:5902 |
Gene name: | CHD5 |
Chromosome: | 1p36.3 |
Previous Symbols: | |
Previous Names: | |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | Rat Genome Database ID: | ||
HGNC ID: | HGNC:16816 | RefSeq IDs: | NM_015557 |
Entrez Gene ID: | 26038 | Ensembl Gene ID: | ENSG00000116254 |
VEGA IDs: | OTTHUMG00000000952 | UniProt ID: | Q8TDI0 |
UCSC ID: | uc001amb.1 | OMIM ID: | 610771 |
Pubmed: | PMID11889561 PMID 12592387 | ||
CCDS IDs: | CCDSCCDS57.1 |
Chromodomain-helicase-DNA-binding protein 5 is an enzyme that in humans is encoded by the CHD5 gene.
Changes in gene expression are associated with changes in chromatin structure, which can result from modification of histones by acetylation and methylation. In addition, SWI/SNF proteins can effect chromatin structure and gene expression by causing ATP-dependent disruption of the nucleosome and by enhancing binding of transcription factors. CHD5 belongs to a group of SWI/SNF proteins called CHD proteins, which contain a SWI/SNF-like helicase/ATPase domain, as well as a DNA-binding domain and a chromodomain that directly modifies chromatin structure (Thompson et al., 2003 [PubMed 12592387]).[supplied by OMIM, Mar 2008]. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: May play a role in the development of the nervous system and the pathogenesis of neural tumors.
Products for CHD5 gene
Catalog | Product Name | Application | Company |
GFS:E05902 | chromodomain helicase DNA binding protein 5; ELISA kit | ELISA | n/a |
GFS:A05902 | chromodomain helicase DNA binding protein 5; Anti | ANTIBODIES | n/a |
GFS:P05902 | chromodomain helicase DNA binding protein 5; Protien | Protien | n/a |