Symbol: Name: ID: |
CCL8 chemokine (C-C motif) ligand 8 GFS:559 |
Gene name: | CCL8 |
Chromosome: | 17q11.2 |
Previous Symbols: | SCYA8 |
Previous Names: | small inducible cytokine subfamily A (Cys-Cys), member 8 (monocyte chemotactic protein 2) |
Aliases: | MCP-2, HC14 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | Rat Genome Database ID: | ||
HGNC ID: | HGNC:10635 | RefSeq IDs: | NM_005623 |
Entrez Gene ID: | 6355 | Ensembl Gene ID: | ENSG00000108700 |
VEGA IDs: | OTTHUMG00000132883 | UniProt ID: | P80075 |
UCSC ID: | uc002hib.2 | OMIM ID: | 602283 |
Pubmed: | PMID9119400 | ||
CCDS IDs: | CCDSCCDS11280.1 |
This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils. By recruiting leukocytes to sites of inflammation this cytokine may contribute to tumor-associated leukocyte infiltration and to the antiviral state against HIV infection. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils. May play a role in neoplasia and inflammatory host responses. This protein can bind heparin. The processed form MCP-2(6-76) does not show monocyte chemotactic activity, but inhibits the chemotactic effect most predominantly of CCL7, and also of CCL2 and CCL5 and CCL8
Products for CCL8 gene
Catalog | Product Name | Application | Company |
GFS:E00559 | chemokine (C-C motif) ligand 8; ELISA kit | ELISA | n/a |
GFS:A00559 | chemokine (C-C motif) ligand 8; Anti | ANTIBODIES | n/a |
GFS:P00559 | chemokine (C-C motif) ligand 8; Protien | Protien | n/a |