Symbol: Name: ID: |
CCL25 chemokine (C-C motif) ligand 25 GFS:548 |
Gene name: | CCL25 |
Chromosome: | 19p13.2 |
Previous Symbols: | SCYA25 |
Previous Names: | small inducible cytokine subfamily A (Cys-Cys), member 25 |
Aliases: | TECK, Ckb15 |
Name Aliases: | Ck beta-15, |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1099448 | Rat Genome Database ID: | RGD:1305530 |
HGNC ID: | HGNC:10624 | RefSeq IDs: | NM_001201359 |
Entrez Gene ID: | 6370 | Ensembl Gene ID: | ENSG00000131142 |
VEGA IDs: | OTTHUMG00000141287 | UniProt ID: | O15444 |
UCSC ID: | uc002mjd.2 | OMIM ID: | 602565 |
Pubmed: | PMID9285413 PMID 9722960 | ||
CCDS IDs: | CCDSCCDS12194.1 |
CCL25 belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for dendritic cells, thymocytes, and activated macrophages but is inactive on peripheral blood lymphocytes and neutrophils. The product of this gene binds to chemokine receptor CCR9. Alternative splicing results in multiple transcript variants. [provided by RefSeq].
Potentially involved in T-cell development. Recombinant protein shows chemotactic activity on thymocytes, macrophages, THP-1 cells, and dendritics cells but is inactive on peripheral blood lymphocytes and neutrophils. Binds to CCR9. Isoform 2 is an antagonist of isoform 1
Products for CCL25 gene
Catalog | Product Name | Application | Company |
GFS:E00548 | chemokine (C-C motif) ligand 25; ELISA kit | ELISA | n/a |
GFS:A00548 | chemokine (C-C motif) ligand 25; Anti | ANTIBODIES | n/a |
GFS:P00548 | chemokine (C-C motif) ligand 25; Protien | Protien | n/a |