Symbol: Name: ID: |
CCL3 chemokine (C-C motif) ligand 3 GFS:551 |
Gene name: | CCL3 |
Chromosome: | 17q12 |
Previous Symbols: | SCYA3 |
Previous Names: | small inducible cytokine A3 (homologous to mouse Mip-1a) |
Aliases: | G0S19-1, LD78ALPHA, MIP-1-alpha |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:98260 | Rat Genome Database ID: | RGD:3647 |
HGNC ID: | HGNC:10627 | RefSeq IDs: | NM_002983 |
Entrez Gene ID: | 6348 | Ensembl Gene ID: | ENSG00000006075 |
VEGA IDs: | OTTHUMG00000133000 | UniProt ID: | P10147 |
UCSC ID: | uc002hkv.2 | OMIM ID: | 182283 |
Pubmed: | |||
CCDS IDs: | CCDSCCDS11307.1 |
Chemokine (C-C motif) ligand 3 (CCL3) is a protein that in humans is encoded by the CCL3 gene.This locus represents a small inducible cytokine. The encoded protein, also known as macrophage inflammatory protein 1 alpha, plays a role in inflammatory responses through binding to the receptors CCR1, CCR4 and CCR5. Polymorphisms at this locus may be associated with both resistance and susceptibility to infection by human immunodeficiency virus type 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV)
Products for CCL3 gene
Catalog | Product Name | Application | Company |
GFS:E00551 | chemokine (C-C motif) ligand 3; ELISA kit | ELISA | n/a |
GFS:A00551 | chemokine (C-C motif) ligand 3; Anti | ANTIBODIES | n/a |
GFS:P00551 | chemokine (C-C motif) ligand 3; Protien | Protien | n/a |