Symbol: Name: ID: |
CCL16 chemokine (C-C motif) ligand 16 GFS:537 |
Gene name: | CCL16 |
Chromosome: | 17q11.2 |
Previous Symbols: | SCYA16 |
Previous Names: | small inducible cytokine subfamily A (Cys-Cys), member 16 |
Aliases: | NCC-4, SCYL4, LEC, HCC-4, LMC, LCC-1, CKb12, Mtn-1 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | Rat Genome Database ID: | ||
HGNC ID: | HGNC:10614 | RefSeq IDs: | NM_004590 |
Entrez Gene ID: | 6360 | Ensembl Gene ID: | ENSG00000161573 |
VEGA IDs: | OTTHUMG00000132999 | UniProt ID: | O15467 |
UCSC ID: | uc002hkl.2 | OMIM ID: | 601394 |
Pubmed: | PMID8661057 | ||
CCDS IDs: | CCDSCCDS11303.1 |
This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for lymphocytes and monocytes but not for neutrophils. This cytokine also shows a potent myelosuppressive activity and suppresses proliferation of myeloid progenitor cells. The expression of this gene is upregulated by IL-10. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Shows chemotactic activity for lymphocytes and monocytes but not neutrophils. Also shows potent myelosuppressive activity, suppresses proliferation of myeloid progenitor cells. Recombinant SCYA16 shows chemotactic activity for monocytes and THP-1 monocytes, but not for resting lymphocytes and neutrophils. Induces a calcium flux in THP-1 cells that were desensitized by prior expression to RANTES
Products for CCL16 gene
Catalog | Product Name | Application | Company |
GFS:E00537 | chemokine (C-C motif) ligand 16; ELISA kit | ELISA | n/a |
GFS:A00537 | chemokine (C-C motif) ligand 16; Anti | ANTIBODIES | n/a |
GFS:P00537 | chemokine (C-C motif) ligand 16; Protien | Protien | n/a |