Symbol: Name: ID: |
CCL21 chemokine (C-C motif) ligand 21 GFS:544 |
Gene name: | CCL21 |
Chromosome: | 9p13 |
Previous Symbols: | SCYA21 |
Previous Names: | small inducible cytokine subfamily A (Cys-Cys), member 21 |
Aliases: | SLC, exodus-2, TCA4, CKb9, 6Ckine, ECL |
Name Aliases: | beta chemokine exodus-2, |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1349182 | Rat Genome Database ID: | RGD:1311996 |
HGNC ID: | HGNC:10620 | RefSeq IDs: | NM_002989 |
Entrez Gene ID: | 6366 | Ensembl Gene ID: | ENSG00000137077 |
VEGA IDs: | OTTHUMG00000019838 | UniProt ID: | O00585 |
UCSC ID: | uc003zvo.2 | OMIM ID: | 602737 |
Pubmed: | PMID9235955 | ||
CCDS IDs: | CCDSCCDS6571.1 |
CCL21 is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. Similar to other chemokines the protein encoded by this gene inhibits hemopoiesis and stimulates chemotaxis. This protein is chemotactic in vitro for thymocytes and activated T cells, but not for B cells, macrophages, or neutrophils. The cytokine encoded by this gene may also play a role in mediating homing of lymphocytes to secondary lymphoid organs. It is a high affinity functional ligand for chemokine receptor 7 (CCR7) that is expressed on T and B lymphocytes and a known receptor for another member of the cytokine family (small inducible cytokine A19). [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Products for CCL21 gene
Catalog | Product Name | Application | Company |
GFS:E00544 | chemokine (C-C motif) ligand 21; ELISA kit | ELISA | n/a |
GFS:A00544 | chemokine (C-C motif) ligand 21; Anti | ANTIBODIES | n/a |
GFS:P00544 | chemokine (C-C motif) ligand 21; Protien | Protien | n/a |