Symbol: Name: ID: |
CCL7 chemokine (C-C motif) ligand 7 GFS:558 |
Gene name: | CCL7 |
Chromosome: | 17q11.2-q12 |
Previous Symbols: | SCYA6, SCYA7 |
Previous Names: | small inducible cytokine A7 (monocyte chemotactic protein 3) |
Aliases: | MCP-3, NC28, FIC, MARC, MCP3 |
Name Aliases: | monocyte chemoattractant protein 3, |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:99512 | Rat Genome Database ID: | RGD:1359152 |
HGNC ID: | HGNC:10634 | RefSeq IDs: | NM_006273 |
Entrez Gene ID: | 6354 | Ensembl Gene ID: | ENSG00000108688 |
VEGA IDs: | OTTHUMG00000132889 | UniProt ID: | P80098 |
UCSC ID: | uc002hhz.2 | OMIM ID: | 158106 |
Pubmed: | PMID8461011 | ||
CCDS IDs: | CCDSCCDS11278.1 |
Chemokine (C-C motif) ligand 7 (CCL7) is a small cytokine known as a chemokine that was previously called monocyte-specific chemokine 3 (MCP3). Due to CCL7 possessing two adjacent N-terminal cysteine residues in its mature protein, it is classified among the subfamily of chemokines known as CC chemokines.This gene encodes monocyte chemotactic protein 3, a secreted chemokine which attracts macrophages during inflammation and metastasis. It is a member of the C-C subfamily of chemokines which are characterized by having two adjacent cysteine residues. The protein is an in vivo substrate of matrix metalloproteinase 2, an enzyme which degrades components of the extracellular matrix. This gene is part of a cluster of C-C chemokine family members on chromosome 17q. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Chemotactic factor that attracts monocytes and eosinophils, but not neutrophils. Augments monocyte anti-tumor activity. Also induces the release of gelatinase B. This protein can bind heparin. Binds to CCR1, CCR2 and CCR3
Products for CCL7 gene
Catalog | Product Name | Application | Company |
GFS:E00558 | chemokine (C-C motif) ligand 7; ELISA kit | ELISA | n/a |
GFS:A00558 | chemokine (C-C motif) ligand 7; Anti | ANTIBODIES | n/a |
GFS:P00558 | chemokine (C-C motif) ligand 7; Protien | Protien | n/a |