Symbol: Name: ID: |
CCL4 chemokine (C-C motif) ligand 4 GFS:555 |
Gene name: | CCL4 |
Chromosome: | 17q21-q23 |
Previous Symbols: | LAG1, SCYA4 |
Previous Names: | small inducible cytokine A4 (homologous to mouse Mip-1b) |
Aliases: | MIP-1-beta, Act-2, AT744.1 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:98261 | Rat Genome Database ID: | RGD:620441 |
HGNC ID: | HGNC:10630 | RefSeq IDs: | NM_002984 |
Entrez Gene ID: | 6351 | Ensembl Gene ID: | ENSG00000129277 |
VEGA IDs: | UniProt ID: | P13236 | |
UCSC ID: | uc002hkw.1 | OMIM ID: | 182284 |
Pubmed: | PMID1972563 | ||
CCDS IDs: | CCDSCCDS11308.1 |
Chemokine (C-C motif) ligand 4, also known as CCL4, is a protein which in humans is encoded by the CCL4 gene.Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T-cells. MIP-1-beta(3-69) is also a ligand for CCR1 and CCR2 isoform B
Products for CCL4 gene
Catalog | Product Name | Application | Company |
GFS:E00555 | chemokine (C-C motif) ligand 4; ELISA kit | ELISA | n/a |
GFS:A00555 | chemokine (C-C motif) ligand 4; Anti | ANTIBODIES | n/a |
GFS:P00555 | chemokine (C-C motif) ligand 4; Protien | Protien | n/a |