Symbol: Name: ID: |
CDC7 cell division cycle 7 homolog (S. cerevisiae) GFS:6500 |
Gene name: | CDC7 |
Chromosome: | 1p22 |
Previous Symbols: | CDC7L1 |
Previous Names: | CDC7 (cell division cycle 7, S. cerevisiae, homolog)-like 1, "CDC7 cell division cycle 7 (S. cerevisiae)", "cell division cycle 7 (S. cerevisiae)" |
Aliases: | Hsk1, huCdc7, HsCdc7 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1309511 | Rat Genome Database ID: | RGD:1308351 |
HGNC ID: | HGNC:1745 | RefSeq IDs: | NM_001134419 |
Entrez Gene ID: | 8317 | Ensembl Gene ID: | ENSG00000097046 |
VEGA IDs: | OTTHUMG00000047810 | UniProt ID: | O00311 |
UCSC ID: | uc001dof.2 | OMIM ID: | 603311 |
Pubmed: | PMID9405610 PMID 9250678 | ||
CCDS IDs: | CCDSCCDS734.1 |
Cell division cycle 7-related protein kinase is an enzyme that in humans is encoded by the CDC7 gene.
This gene encodes a cell division cycle protein with kinase activity that is critical for the G1/S transition. The yeast homolog is also essential for initiation of DNA replication as cell division occurs. Overexpression of this gene product may be associated with neoplastic transformation for some tumors. Multiple alternatively spliced transcript variants that encode the same protein have been detected. [provided by RefSeq, Aug 2008].
Function: Seems to phosphorylate critical substrates that regulate the G1/S phase transition and/or DNA replication. Can phosphorylates MCM2 and MCM3.
Products for CDC7 gene
Catalog | Product Name | Application | Company |
GFS:E06500 | cell division cycle 7 homolog (S. cerevisiae); ELISA kit | ELISA | n/a |
GFS:A06500 | cell division cycle 7 homolog (S. cerevisiae); Anti | ANTIBODIES | n/a |
GFS:P06500 | cell division cycle 7 homolog (S. cerevisiae); Protien | Protien | n/a |