Symbol: Name: ID: |
CDCA7 cell division cycle associated 7 GFS:3921 |
Gene name: | CDCA7 |
Chromosome: | 2q31.1 |
Previous Symbols: | |
Previous Names: | |
Aliases: | FLJ14736, JPO1 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1914203 | Rat Genome Database ID: | RGD:1309363 |
HGNC ID: | HGNC:14628 | RefSeq IDs: | NM_031942 |
Entrez Gene ID: | 83879 | Ensembl Gene ID: | ENSG00000144354 |
VEGA IDs: | OTTHUMG00000132296 | UniProt ID: | Q9BWT1 |
UCSC ID: | uc002uic.1 | OMIM ID: | 609937 |
Pubmed: | PMID11598121 PMID 12188893 | ||
CCDS IDs: | CCDSCCDS2252.1 CCDS CCDS2253.1 |
Cell division cycle-associated protein 7 is a protein that in humans is encoded by the CDCA7 gene.
This gene was identified as a c-Myc responsive gene, and behaves as a direct c-Myc target gene. Overexpression of this gene is found to enhance the transformation of lymphoblastoid cells, and it complements a transformation-defective Myc Box II mutant, suggesting its involvement in c-Myc-mediated cell transformation. Two alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008].
Function: Participates in MYC-mediated cell transformation; induces anchorage-independent growth and clonogenicity in lymphoblastoid cells. Insufficient to induce tumorigenicity when overexpressed but contributes to MYC-mediated tumorigenesis. May play a role as transcriptional regulator.
Products for CDCA7 gene
Catalog | Product Name | Application | Company |
GFS:E03921 | cell division cycle associated 7; ELISA kit | ELISA | n/a |
GFS:A03921 | cell division cycle associated 7; Anti | ANTIBODIES | n/a |
GFS:P03921 | cell division cycle associated 7; Protien | Protien | n/a |