| Symbol: Name: ID: |
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2 GFS:5391 |
| Gene name: | CDC42EP2 |
| Chromosome: | 11q13 |
| Previous Symbols: | |
| Previous Names: | |
| Aliases: | CEP2, BORG1 |
| Name Aliases: | CRIB-containing BOGR1 protein |
| Locus Type: | gene with protein product |
| Mouse Genome Database ID: | MGI:1929744 | Rat Genome Database ID: | RGD:1310253 |
| HGNC ID: | HGNC:16263 | RefSeq IDs: | NM_006779 |
| Entrez Gene ID: | 10435 | Ensembl Gene ID: | ENSG00000149798 |
| VEGA IDs: | UniProt ID: | O14613 | |
| UCSC ID: | uc001odl.2 | OMIM ID: | 606132 |
| Pubmed: | PMID10490598 PMID 11035016 | ||
| CCDS IDs: | CCDSCCDS8099.1 | ||
Cdc42 effector protein 2 is a protein that in humans is encoded by the CDC42EP2 gene.
CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of CDC42. Coexpression of this protein with CDC42 suggested a role of this protein in actin filament assembly and cell shape control. [provided by RefSeq, Aug 2011].
Function: Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts in a CDC42-dependent manner.
Products for CDC42EP2 gene
| Catalog | Product Name | Application | Company |
| GFS:E05391 | CDC42 effector protein (Rho GTPase binding) 2; ELISA kit | ELISA | n/a |
| GFS:A05391 | CDC42 effector protein (Rho GTPase binding) 2; Anti | ANTIBODIES | n/a |
| GFS:P05391 | CDC42 effector protein (Rho GTPase binding) 2; Protien | Protien | n/a |
