Symbol: Name: ID: |
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4 GFS:6234 |
Gene name: | CDC42EP4 |
Chromosome: | 17q24-q25 |
Previous Symbols: | |
Previous Names: | |
Aliases: | CEP4, KAIA1777, BORG4, MGC3740, MGC17125 |
Name Aliases: | Cdc42 effector protein 4, |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1929760 | Rat Genome Database ID: | RGD:1311567 |
HGNC ID: | HGNC:17147 | RefSeq IDs: | NM_012121 |
Entrez Gene ID: | 23580 | Ensembl Gene ID: | ENSG00000179604 |
VEGA IDs: | UniProt ID: | Q9H3Q1 | |
UCSC ID: | uc002jjo.2 | OMIM ID: | 605468 |
Pubmed: | PMID11035016 PMID 10490598 | ||
CCDS IDs: | CCDSCCDS11695.1 |
Cdc42 effector protein 4 is a protein that in humans is encoded by the CDC42EP4 gene.
The product of this gene is a member of the CDC42-binding protein family. Members of this family interact with Rho family GTPases and regulate the organization of the actin cytoskeleton. This protein has been shown to bind both CDC42 and TC10 GTPases in a GTP-dependent manner. When overexpressed in fibroblasts, this protein was able to induce pseudopodia formation, which suggested a role in inducing actin filament assembly and cell shape control. [provided by RefSeq, Jul 2008].
Function: Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation, when overexpressed in fibroblasts.
Products for CDC42EP4 gene
Catalog | Product Name | Application | Company |
GFS:E06234 | CDC42 effector protein (Rho GTPase binding) 4; ELISA kit | ELISA | n/a |
GFS:A06234 | CDC42 effector protein (Rho GTPase binding) 4; Anti | ANTIBODIES | n/a |
GFS:P06234 | CDC42 effector protein (Rho GTPase binding) 4; Protien | Protien | n/a |