Symbol: Name: ID: |
CDC6 cell division cycle 6 homolog (S. cerevisiae) GFS:6491 |
Gene name: | CDC6 |
Chromosome: | 17q21.3 |
Previous Symbols: | CDC18L |
Previous Names: | CDC6 (cell division cycle 6, S. cerevisiae) homolog, "CDC6 cell division cycle 6 homolog (S. cerevisiae)" |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1345150 | Rat Genome Database ID: | RGD:1309157 |
HGNC ID: | HGNC:1744 | RefSeq IDs: | NM_001254 |
Entrez Gene ID: | 990 | Ensembl Gene ID: | ENSG00000094804 |
VEGA IDs: | OTTHUMG00000133324 | UniProt ID: | Q99741 |
UCSC ID: | uc002huj.1 | OMIM ID: | 602627 |
Pubmed: | PMID8990175 PMID 9566895 | ||
CCDS IDs: | CCDSCCDS11365.1 |
Cell division control protein 6 homolog is a protein that in humans is encoded by the CDC6 gene.
The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated.
Products for CDC6 gene
Catalog | Product Name | Application | Company |
GFS:E06491 | cell division cycle 6 homolog (S. cerevisiae); ELISA kit | ELISA | n/a |
GFS:A06491 | cell division cycle 6 homolog (S. cerevisiae); Anti | ANTIBODIES | n/a |
GFS:P06491 | cell division cycle 6 homolog (S. cerevisiae); Protien | Protien | n/a |