| Symbol: Name: ID: |
CDC37 cell division cycle 37 homolog (S. cerevisiae) GFS:6428 |
| Gene name: | CDC37 |
| Chromosome: | 19p13.2 |
| Previous Symbols: | |
| Previous Names: | CDC37 (cell division cycle 37, S. cerevisiae, homolog), "CDC37 cell division cycle 37 homolog (S. cerevisiae)" |
| Aliases: | P50CDC37 |
| Name Aliases: | CDC37 cell division cycle 37 homolog, |
| Locus Type: | gene with protein product |
| Mouse Genome Database ID: | MGI:109531 | Rat Genome Database ID: | RGD:71006 |
| HGNC ID: | HGNC:1735 | RefSeq IDs: | NM_007065 |
| Entrez Gene ID: | 11140 | Ensembl Gene ID: | ENSG00000105401 |
| VEGA IDs: | UniProt ID: | Q16543 | |
| UCSC ID: | uc002mof.1 | OMIM ID: | 605065 |
| Pubmed: | PMID8703009 PMID 8666233 | ||
| CCDS IDs: | CCDSCCDS12237.1 | ||
Hsp90 co-chaperone Cdc37 is a protein that in humans is encoded by the CDC37 gene.
The protein encoded by this gene is highly similar to Cdc 37, a cell division cycle control protein of Sacchromyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF-1, MOK, as well as eIF2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, resulting in stabilization and promotion of their activity.
Products for CDC37 gene
| Catalog | Product Name | Application | Company |
| GFS:E06428 | cell division cycle 37 homolog (S. cerevisiae); ELISA kit | ELISA | n/a |
| GFS:A06428 | cell division cycle 37 homolog (S. cerevisiae); Anti | ANTIBODIES | n/a |
| GFS:P06428 | cell division cycle 37 homolog (S. cerevisiae); Protien | Protien | n/a |
