Symbol: Name: ID: |
CDC26 cell division cycle 26 homolog (S. cerevisiae) GFS:6739 |
Gene name: | CDC26 |
Chromosome: | 9q32 |
Previous Symbols: | C9orf17 |
Previous Names: | chromosome 9 open reading frame 17, "cell division cycle 26" |
Aliases: | APC12, ANAPC12 |
Name Aliases: | CDC26 subunit of anaphase promoting complex, |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1913690 | Rat Genome Database ID: | RGD:1311342 |
HGNC ID: | HGNC:17839 | RefSeq IDs: | NM_139286 |
Entrez Gene ID: | 246184 | Ensembl Gene ID: | ENSG00000176386 |
VEGA IDs: | OTTHUMG00000020521 | UniProt ID: | Q8NHZ8 |
UCSC ID: | uc004bgw.2 | OMIM ID: | |
Pubmed: | PMID8895471 PMID 10922056 | ||
CCDS IDs: | CCDSCCDS6790.1 |
The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc26, a component of cell cycle anaphase-promoting complex (APC). APC is composed of a group of highly conserved proteins and functions as a cell cycle-regulated ubiquitin-protein ligase. APC thus is responsible for the cell cycle regulated proteolysis of various proteins. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. May recruit the E2 ubiquitin-conjugating enzymes to the complex.
Products for CDC26 gene
Catalog | Product Name | Application | Company |
GFS:E06739 | cell division cycle 26 homolog (S. cerevisiae); ELISA kit | ELISA | n/a |
GFS:A06739 | cell division cycle 26 homolog (S. cerevisiae); Anti | ANTIBODIES | n/a |
GFS:P06739 | cell division cycle 26 homolog (S. cerevisiae); Protien | Protien | n/a |