Symbol: Name: ID: |
CDC25C cell division cycle 25 homolog C (S. pombe) GFS:6351 |
Gene name: | CDC25C |
Chromosome: | 5q31 |
Previous Symbols: | CDC25 |
Previous Names: | cell division cycle 25C, "cell division cycle 25 homolog C (S. cerevisiae)" |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:88350 | Rat Genome Database ID: | RGD:1311875 |
HGNC ID: | HGNC:1727 | RefSeq IDs: | NM_001790 |
Entrez Gene ID: | 995 | Ensembl Gene ID: | ENSG00000158402 |
VEGA IDs: | OTTHUMG00000129203 | UniProt ID: | P30307 |
UCSC ID: | uc003lcp.1 | OMIM ID: | 157680 |
Pubmed: | PMID1703321 | ||
CCDS IDs: | CCDSCCDS4202.1 CCDS CCDS4203.1 |
M-phase inducer phosphatase 3 is an enzyme that in humans is encoded by the CDC25C gene.
This gene is highly conserved during evolution and it plays a key role in the regulation of cell division. The encoded protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known. [provided by RefSeq, Jul 2008].
Function: Functions as a dosage-dependent inducer in mitotic control. It is a tyrosine protein phosphatase required for progression of the cell cycle. It directly dephosphorylates CDK1 and activate its kinase activity.
Products for CDC25C gene
Catalog | Product Name | Application | Company |
GFS:E06351 | cell division cycle 25 homolog C (S. pombe); ELISA kit | ELISA | n/a |
GFS:A06351 | cell division cycle 25 homolog C (S. pombe); Anti | ANTIBODIES | n/a |
GFS:P06351 | cell division cycle 25 homolog C (S. pombe); Protien | Protien | n/a |