| Symbol: Name: ID: |
CDC20 cell division cycle 20 homolog (S. cerevisiae) GFS:6316 |
| Gene name: | CDC20 |
| Chromosome: | 1p34.1 |
| Previous Symbols: | |
| Previous Names: | CDC20 (cell division cycle 20, S. cerevisiae, homolog), "CDC20 cell division cycle 20 homolog (S. cerevisiae)" |
| Aliases: | p55CDC, CDC20A |
| Name Aliases: | |
| Locus Type: | gene with protein product |
| Mouse Genome Database ID: | MGI:1859866 | Rat Genome Database ID: | RGD:620477 |
| HGNC ID: | HGNC:1723 | RefSeq IDs: | NM_001255 |
| Entrez Gene ID: | 991 | Ensembl Gene ID: | ENSG00000117399 |
| VEGA IDs: | OTTHUMG00000007420 | UniProt ID: | Q12834 |
| UCSC ID: | uc001cix.2 | OMIM ID: | 603618 |
| Pubmed: | PMID7513050 PMID 9353311 | ||
| CCDS IDs: | CCDSCCDS484.1 | ||
The cell-division cycle protein 20 is an essential regulator of cell division that is encoded by the CDC20 gene in humans.
CDC20 appears to act as a regulatory protein interacting with several other proteins at multiple points in the cell cycle. It is required for two microtubule-dependent processes, nuclear movement prior to anaphase and chromosome separation. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Required for full ubiquitin ligase activity of the anaphase promoting complex/cyclosome (APC/C) and may confer substrate specificity upon the complex. Is regulated by MAD2L1. In metaphase the MAD2L1-CDC20-APC/C ternary complex is inactive and in anaphase the CDC20-APC/C binary complex is active in degrading substrates.
Products for CDC20 gene
| Catalog | Product Name | Application | Company |
| GFS:E06316 | cell division cycle 20 homolog (S. cerevisiae); ELISA kit | ELISA | n/a |
| GFS:A06316 | cell division cycle 20 homolog (S. cerevisiae); Anti | ANTIBODIES | n/a |
| GFS:P06316 | cell division cycle 20 homolog (S. cerevisiae); Protien | Protien | n/a |
